Umfanekiso oPhambili we-Ibrutinib 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

I-Ibrutinib ePhakathi 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Inkcazo emfutshane:

Inombolo yeKhathalogu. SZ-2028

I-CAS: 330786-24-8

Ubumsulwa: 99%

Ukusetyenziswa kwe-Ibrutinib

Iselfowuni/iWechat/iWhatsApp: +86-13681683526

I-imeyile:lchen@syncozymes.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo:

I-SyncoZymes (Shanghai) Co., Ltd. ngumvelisi ophambili kunye nomthengisi we-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) ngomgangatho ophezulu. Singabonelela nge-COA, ukuhanjiswa kwihlabathi liphela, ubungakanani obuncinci nobuncinci obufumanekayo. Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha oluquka inombolo ye-CAS, igama lemveliso, ubungakanani kuthi. Nceda unxibelelane nathi:lchen@syncozymes.com

Iipropati zeKhemikhali:

Indawo yokunyibilika	>262oC (ngoDisemba)
Indawo yokubila	577.4±50.0 °C (Kuqikelelwe)
uxinano	1.380±0.06 g/cm3 (Kuqikelelwe)
ubushushu bokugcina.	Gcina kwindawo emnyama, umoya ongcolileyo, ubushushu begumbi
ukunyibilika	I-DMSO (Kancinci), i-Ethanol (Kancinci)
i-pka	10.40±0.30(Kuqikelelwe)
ifomu	Iqinile
umbala	Ukusuka kumbala omdaka okhanyayo ukuya kumbala omdaka okhanyayo

Iphakheji kunye noGcino:

Iphakheji:Ibhotile, ibhegi yefoyile ye-aluminium, i-25kg/iDrum yekhadibhodi, okanye ngokweemfuno zomthengi.

Imeko Yokugcina:Gcina kwindawo emnyama, umoya ongcolileyo, ubushushu begumbi.

Isicelo:

I-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) sisixhobo esisebenzayo sokudibanisa amayeza, esisetyenziswa njengesixhobo esiphakathi samayeza.

Ngaphambili: I-Ibrutinib Intermediate (S)-1-Boc-3-hydroxypiperidine

Okulandelayo: I-Ibrutinib Intermediate 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

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