i-β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
I-SyncoZymes (Shanghai) Co., Ltd. ngumvelisi ophambili kunye nomthengisi we-β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) ngomgangatho ophezulu. Singabonelela nge-COA, ukuhanjiswa kwihlabathi liphela, ubungakanani obuncinci nobuncinci obufumanekayo. Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha oluquka inombolo ye-CAS, igama lemveliso, ubungakanani kuthi. Nceda unxibelelane nathi:lchen@syncozymes.com
| Igama leKhemikhali | i-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Izithethantonye | i-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Inombolo ye-CAS | 53-59-8 |
| Ubunzima beMolekyuli | 743.41 |
| Ifomula yeMolekyuli | C21H28N7O17P3 |
| Inombolo ye-EINECS | 200-178-1 |
| ubushushu bokugcina. | Gcina kwindawo emnyama, emoyeni ongcolileyo, kwifriji, ngaphantsi kwe -20°C |
| ukunyibilika | I-H2O: 50 mg/mL, icacile, imthubi kancinci |
| i-pka | pKa1 3.9; pKa2 6.1 (kwi-25℃) |
| ubuninzi be-λ | 260nm (elikhanyayo) |
| I-Merck | 14,6348 |
| Inkqubo yoBhaliso lweZinto zeEPA | I-Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), i-P'.fwdarw.5'-ester ene-3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, ityuwa yangaphakathi (53-59-8) |
| Into yoVavanyo | Iinkcukacha |
| Inkangeleko | Umgubo omhlophe ukuya kotyheli |
| Ukunyibilika | 200mg/ml emanzini |
| Ixabiso le-pH (100mg/ml) | 5.0～7.0 |
| Uhlalutyo lwe-UV Spectral εkwi-260 nm kunye ne-pH 7.5 | (18±1.0)×10³L/mol/cm |
| Umxholo (ngohlalutyo lwe-enzyme kunye ne-G6I-PDH kwi-pH 7.5, kusetyenziswa i-spectrophotometer, i-abs.340nm, ngokusekelwe kwi-anhydrous) | ≥90.0% |
| Ubumsulwa (ngokwe-HPLC, %indawo) | ≥95.0% |
| Umthamo wamanzi (ngokwe-KF) | ≤5% |
Iphakheji:Ibhotile, ibhegi yefoyile ye-aluminium, i-25kg/iDrum yekhadibhodi, okanye ngokweemfuno zomthengi.
Imeko Yokugcina:Gcina ivalwe ngokuqinileyo ebumnyameni, ukuze igcinwe ixesha elide, yigcine kwi-2 ~ 8℃.
I-NADP yi-coenzyme, into apho i-nicotinamide adenine dinucleotide kunye nemolekyuli ye-phosphate zibotshelelwe yi-ester bond, kwaye zikhona ngokubanzikwihlabathi lebhayoloji. Iimpawu zayo zeekhemikhali, i-spectrum yokufunxa, uhlobo lwe-redox, njl.njl. zifana ne-NAD (Coenzyme I). I-NADP ingasetyenziswa kakhulu kwiimpenduloivuselelwa zii-dehydrogenases ezahlukeneyo zotywala, ii-ketoreductases kunye nezinye ii-oxidoreductases. Ezifana nezi: inokuncitshiswa ibe yi-NADPH zii-dehydrogenases ezininzi ezifananjenge-6-phosphoglucose dehydrogenase (EC.1.1.1.49), i-6-phosphogluconate dehydrogenase (EC.1.1.1.44). Nangona kunjalo, ayinakukwazi ukusabela kwiintlobo ezininzi ze-enzymes.ii-dehydrogenases ezisebenzisa i-NAD, kwaye azinakukwazi ukunyibilikiswa ngokuthe ngqo yikhonkco lokuphefumla. Ngokungafaniyo ne-NAD, ikhona ikakhulu kwimeko enciphileyo kwiiseli zezinto eziphilayo ze-aerobic.
Ngokwendlela esetyenziswa ngayo imveliso, ingahlulwahlulwa ibe ngamanqanaba alandelayo: ibanga le-biotransformation, ibanga le-diagnostic reagent, ibanga lokutya okunempilo.
Inqanaba lokuguqulwa kwezinto eziphilayo: Ingasetyenziselwa ukwenziwa kwezinto eziphakathi kwamayeza kunye nee-API, ikakhulu ngee-enzymes ze-catalytic, ezifana ne-ketoreductase (KRED),I-P450 monooxygenase (CYP), i-formate dehydrogenase (FDH), i-glucose dehydrogenase (GDH), njl. Linda.
Uhlobo lwe-reagent yokuxilonga: Ineentlobo ngeentlobo zee-enzyme zokuxilonga, njengezinto ezisetyenziswa kwiikiti zokuxilonga.
Udidi lokutya okunempilo: Ukusetyenziswa kwe-NADP yesongezelelo sokutya ikakhulu kukwinkqubo yophando nophuhliso.
