SyncoZymes

iimveliso

I-β-Nicotinamide Mononucleotide (NMN)

Inkcazelo emfutshane:

Igama leMichiza: β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Emhlophe ukuya kumhlophe-umgubo wekristale

Umgangatho ophezulu, iMveliso yoRhwebo

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyile:lchen@syncozymes.com


Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo:

Kutshanje, kukho iindaba ezilungileyo kwintsimi ye-NMN - emva kokuphononongwa ngokungqongqo yikomiti yeengcali ze-US Food and Drug Administration (FDA) umbutho ogunyazisiweyo, izixhobo ze-NMN ze-Shangke Biopharmaceutical (Shanghai) Co., Ltd. ukuya njenge "Shangke Bio") ivunyiwe yi-United States imvume ye-FDA NDI iqinisekisa ukuba izinto zayo eziluhlaza ze-NMN zingasetyenziswa ngokusemthethweni kwimveliso, ukuthengisa kunye nokukhuthaza izongezo zokutya e-United States, kwaye inokufumaneka kwigosa le-FDA. Iwebhusayithi njengesongezelelo sesondlo esitsha semathiriyeli ekrwada, inombolo 1247.

I-FDA NDI yeyona nkqubo ibalulekileyo yokuqinisekisa kwiimarike zase-US.Ukufumana esi satifikethi akuthethi nje ukuba ukhuseleko kunye nomgangatho weemveliso ze-Shangke Bio ziyamkelwa kakhulu, kodwa ikwaluncedo kuphuhliso olusemgangathweni oluqhubekayo loshishino lwe-NMN ekuhambeni kwexesha.

Iinkcazelo ngeMichiza:

Igama leMchiza β-Nicotinamide Mononucleotide
Izithethantonye NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE
Inombolo yeCAS 1094-61-7
Ubunzima beMolekyuli 334.22
Ifomula yeemolekyuli I-C11H15N2O8P
EINECS: 214-136-5
Indawo yokunyibilika 166 °C(dec.)
ixesha lokugcina. -20°C
ukunyibilika I-DMSO (Kancinci, ishushu), iMethanol (Kancinci), Amanzi (Kancinci)
ifomu Iqinile
umbala Mhlophe ukuya kumthubi
Merck 13,6697
I-BRN 3570187
Uzinzo: I-Hygroscopic kakhulu
I-InChIKey I-DAYLJWODMCOQEW-TURQNECASA-N

Iinkcukacha:

Into yovavanyo Iinkcukacha
Imbonakalo Umgubo wekristale omhlophe ukuya kumhlophe
Umxholo wesodium ≤1%
ixabiso pH (100mg/ml) 2.0~4.0
Ubunyulu ≥99.0%
Isiqulatho samanzi ≤1%
Iintsimbi ezinzima <10ppm
Arsenic <0.5ppm
Inkokeli <0.5ppm
IMercury <0.1ppm
I-Cadmium <0.5ppm
Intsalela yokunyibilikisa I-Ethanol≤1000ppm
Ubalo lweAerobic Microbial iyonke <750cfu/g
Igwele kunye noMngundo <25cfu/g
I-coliform epheleleyo ≤0.92MPN/g
E. Coli Ibi
Salmonella Ibi
Staph.Aureus Ibi
Uvavanyo (kwisiseko se-anhydrous) ≥99.0%
Izinga lokucoca ≥95%
Unizi lolwapho kuyiwa khona Ingxelo yolwazi

Ukupakishwa kunye noGcino:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Londoloza kwizikhongozeli eziqinile, ezikwaziyo ukumelana nokukhanya, ukwenzela ukugcina ixesha elide ku-2–8°C okanye ngaphantsi.

Isicelo:

I-Nicotinamide Mononucleotide (NMN) yinguqulelo entsha ye-vitamin B3 eyi-1 yesinyathelo esandulelayo kwi-NAD + (iNicotinamide Adenine Dinucleotide).I-NMN yeyokuqala i-NAD+ ebuyisela iselula ukuba ingqinwe iyasebenza ukubuyisela iiseli kwi-vivo.

INicotinamide Adenine Dinucleotide (NAD) yenye yezona molekyuli zibalulekileyo kwaye zinomdla emzimbeni.Iyadingeka ngaphezu kwe-500 yokuphendula kwe-enzymatic kwaye idlala indima ebalulekileyo ekulawuleni phantse zonke iinkqubo zebhayoloji eziphambili (Ansari noRaghava, 2010).Ngaphezu kwako konke, kunokusivumela ukuba siphile ubomi obusempilweni nobude obude.

I-Nicotinamide Adenine Dinucleotide (NAD) ikhona nokuba ikwimo yayo ene-oxidized (NAD+) okanye ifom encitshisiweyo (NADH), eziyi-cofactors ezibalulekileyo zenani le-oxireductases.

I-SyncoZyems njengowokuqala ukufumana i-FDA NDINMN evunyiweyo yeshishini lokuvelisa izinto ekrwada, imele igosa le-FDA lamkele i-NMN njengohlobo olutsha lwezinto ezinokuqala ukwamkelwa kwaye zivunywe kwizithako ezongezelelweyo zokutya e-United States.


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