I-β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) kunye nomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Nceda uqhagamshelane:lchen@syncozymes.com
| Igama leMchiza | I-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Izithethantonye | I-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Inombolo yeCAS | 53-59-8 |
| Ubunzima beMolekyuli | 743.41 |
| Ifomula yeemolekyuli | I-C21H28N7O17P3 |
| I-EINECS No. | 200-178-1 |
| ixesha lokugcina. | Gcina kwindawo emnyama, umoya ongangeni, Gcina kwisikhenkcisi, ngaphantsi kwe -20°C |
| ukunyibilika | H2O: 50 mg/mL, ecacileyo, etyheli kancinane |
| pka | pKa1 3.9;pKa2 6.1(ku-25℃) |
| λmax | 260nm(lit.) |
| Merck | 14,6348 |
| EPA Substance Registry System | I-Adenosine 5'- (trihydrogen diphosphate), 2'- (dihydrogen phosphate), P'.fwdarw.5'-ester kunye ne-3-(aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, ityuwa yangaphakathi (53-59- 8) |
| Into yovavanyo | Iinkcukacha |
| Imbonakalo | Umgubo omhlophe ukuya kumthubi |
| Ukunyibilika | 200mg/ml emanzini |
| ixabiso pH (100mg/ml) | 5.0 ~ 7.0 |
| Uhlalutyo lwe-UV Spectral i-eat 260 nm kunye ne-pH 7.5 | (18±1.0)×10³L/mol/cm |
| Umxholo (ngohlalutyo lwe-enzymatic kunye no-G6I-PDH kwi-pH 7.5, usebenzisa i-spectrophotometer, i-abs.340nm, kwisiseko se-anhydrous) | ≥90.0% |
| Ubunyulu (nge-HPLC, % indawo) | ≥95.0% |
| Isiqulatho samanzi (nge-KF) | ≤5% |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina ubambekile ebumnyameni, kuba ugcino ixesha elide gcina ku-2~8℃.
I-NADP yi-coenzyme, eyinto apho i-nicotinamide adenine dinucleotide kunye nemolekyuli ye-phosphate zibotshwa yi-ester bond, kwaye ikhona ngokubanzi.kwihlabathi lebhayoloji.Iimpawu zayo zeekhemikhali, i-spectrum yokufunxa, ifom ye-redox, njl. zifana ne-NAD (Coenzyme I).I-NADP inokusetyenziswa ngokubanzi kwiimpenduloI-catalyzed yi-alcohol dehydrogenases eyahlukeneyo, i-ketoreductases kunye nezinye ii-oxidoreductases.Okunje: inokuncitshiswa ibe yi-NADPH ngamaninzi dehydrogenases anjalonjenge-6-phosphoglucose dehydrogenase (EC.1.1.1.49), i-6-phosphogluconate dehydrogenase (EC.1.1.1.44).Nangona kunjalo, akunyanzelekanga ukuba ikwazi ukusabela ngabaninziI-dehydrogenases esebenzisa i-NAD, kwaye ayinakukhuselwa ngokuthe ngqo yityathanga lokuphefumla.Ngokungafaniyo ne-NAD, ikhona ikakhulu kwimeko encitshisiweyo kwiiseli zezinto eziphilayo.
Ngokusetyenziswa kwemveliso, inokwahlulwa ngokwala mabanga alandelayo: ibakala le-biotransformation, ibakala lokuxilonga i-reagent, ibakala lokutya kwezempilo.
Ibanga le-Biotransformation: Ingasetyenziselwa ukuhlanganiswa kwe-pharmaceutical intermediates kunye ne-APIs, ngokukodwa nge-catalytic enzymes, njenge-ketoreductase (KRED),I-P450 monooxygenase (CYP), i-formate dehydrogenase (FDH), i-glucose dehydrogenase (GDH), njl. Linda.
I-Diagnostic reagent grade: Ngeentlobo ezahlukeneyo ze-enzymes zokuxilonga, njengezinto ezibonakalayo zeekiti zokuxilonga.
Ibanga lokutya okunempilo: Ukusetyenziswa kwesondlo sokutya kwe-NADP ikakhulu kuphando kunye nenkqubo yophuhliso.
