I-β-Nicotinamide adenine dinucleotide phosphate, ifom ye-oxidized, ityuwa ye-monosodium (i-Reagent Grade II) (NADP ▪NA)
I-SyncoZymes (i-Shanghai) Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-β-Nicotinamide adenine dinucleotide phosphate, ifom ye-oxidized, ityuwa ye-monosodium (i-Reagent Grade II) (i-CAS: 1184-16-3) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Nceda uqhagamshelane:lchen@syncozymes.com
Igama leMchiza | β-Nicotinamide adenine dinucleotide phosphate, ifomu oxidized, ityuwa monosodium |
Izithethantonye | I-β-Nicotinamide adenine dinucleotide phosphate, ifom ye-oxidized, ityuwa ye-monosodium (i-Reagent Grade II) |
Inombolo yeCAS | 1184-16-3 |
Ubunzima beMolekyuli | 765.39 |
Ifomula yeemolekyuli | I-C21H27N7NaO17P3 |
EINECS: | 214-664-6 |
Indawo yokunyibilika | 175-178 °C (dec.)(lit.) |
ixesha lokugcina. | -20°C |
ukunyibilika | H2O: 50 mg/mL |
ifomu | umgubo |
umbala | ukusuka-mhlophe ukuya kumthubi |
Ukunyibilika kwamanzi | Inyibilika emanzini. |
Merck | 14,6344 |
I-BRN | 4779954 |
InChIKey | JNUMDLCHLVUHFS-QYZPTAICSA-M |
Into yovavanyo | Iinkcukacha |
Imbonakalo | Umgubo omhlophe ukuya kumthubi |
Ukunyibilika | 200mg/ml emanzini |
ixabiso pH (100mg/ml) | 3.0 ~ 5.0 |
Uhlalutyo lwe-UV Spectral i-eat 260 nm kunye ne-pH 7.5 | (18±1.0)×10³L/mol/cm |
Umxholo (ngohlalutyo lwe-enzymatic kunye no-G6I-PDH kwi-pH 7.5, usebenzisa i-spectrophotometer, i-abs.340nm, kwisiseko se-anhydrous) | ≥93.0% |
Ubunyulu (nge-HPLC, % indawo) | ≥97.0% |
Isiqulatho samanzi (nge-KF) | ≤5% |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina ubambekile ebumnyameni, kuba ugcino ixesha elide gcina ku-2~8℃.
I-NADP, i-coenzyme, yinto ethi i-nicotinamide adenine dinucleotide ibotshelelwe kwimolekyuli ye-phosphoric acid nge-ester bond, kwaye ikho ngokubanzi kwihlabathi lebhayoloji.Iimpawu zayo zeekhemikhali, i-spectrum yokufunxa kunye nefom ye-redox ifana ne-NAD (coenzyme I).I-NADP inokusetyenziswa ngokubanzi kwiimpendulo ezahlukeneyo ezenziwe nge-oxidoreductases ezifana ne-alcohol dehydrogenase kunye ne-ketoreductase.Ngokomzekelo, inokwehliswa kwi-NADPH ngamaninzi e-dehydrogenases afana ne-glucose 6-phosphate dehydrogenase (EC.1.1.1.44) kunye ne-glucose 6-phosphate dehydrogenase (EC.1.1.44).Nangona kunjalo, ayifuni kusabela ngee-dehydrogenases ezininzi zisebenzisa i-NAD, kwaye ayinako i-oxidize ngokuthe ngqo ikhonkco lokuphefumla.Ngokungafaniyo ne-NAD kwiiseli zezinto eziphilayo ze-aerobic, ubukhulu becala ikhona kwimeko encitshisiweyo.Ngokutsho kokusetyenziswa kwemveliso, inokwahlulwa ibe ngamabakala alandelayo: ibakala le-biotransformation, ibakala lokuxilonga i-reagent kunye nebakala lokutya.