β- Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt (ifomu encitshisiweyo) (NADPH)
I-NADPH sisithako esibizwa ngokuba yi-phosphorylated derivative ye-nicotinamide adenine dinucleotide (NAD) kwindawo eyi-2' yenkqubo yeribose ring edibene ne-adenine kwaye ibandakanyeka kwiimpendulo ezahlukeneyo ze-anabolic,njengokwenziwa kwee-lipids, ii-fatty acids kunye nee-nucleotides. Ezi mpendulo zifuna i-NADPH njenge-reducing agent kunye ne-hydride donor.
Ngokwendlela esetyenziswa ngayo imveliso, ingahlulwahlulwa ibe ngamanqanaba alandelayo: ibanga le-biotransformation, ibanga le-diagnostic reagent.
Inqanaba lokuguqulwa kwezinto eziphilayo: Ingasetyenziselwa ukwenziwa kwezinto eziphakathi kwamayeza kunye nee-API, ikakhulu ngokusebenzisana nee-enzymes ze-catalytic. Okwangoku, iphandwa kakhulu kwinqanaba lelebhu.
Uhlobo lwe-reagent yokuxilonga: Isetyenziswa kunye nee-enzymes ezahlukeneyo zokuxilonga njengezinto ezisetyenziswa kwiikiti zokuxilonga.
Inzuzo yethu kwimarike
① Ukwenziwa kwezinto eziphilayo, ukhuseleko oluluhlaza nolwendalo, ngokuhambelana neemfuno zangoku zokhuseleko lwendalo ekhaya nakwamanye amazwe.
② Ixabiso eliphantsi kunye nexabiso lokuthengisa elinenzuzo.
③ Ubonelelo oluzinzileyo, unikezelo lwesitokhwe oluhlala ixesha elide.
| Igama leKhemikhali | I-NADPH |
| Izithethantonye | β- Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt (ifomu encitshisiweyo) |
| Inombolo ye-CAS | 2646-71-1 |
| Ubunzima beMolekyuli | 769.42 |
| Ifomula yeMolekyuli | C21H31N7NaO17P3 |
| EINECS: | 220-163-3 |
| Indawo yokunyibilika | >250°C (ngoDisemba) |
| ubushushu bokugcina. | Gcina kwindawo emnyama, emoyeni ongcolileyo, kwifriji, ngaphantsi kwe -20°C |
| ukunyibilika | I-10 mM NaOH: enyibilikayo i-50mg/mL, icacile |
| ifomu | Umgubo |
| umbala | Umhlophe ukuya kumhlophe ongekho mhlophe |
| I-Merck | 14,6348 |
| Uzinzo lwaManzi: | Iyanyibilika emanzini (50 mg/ml). |
| Ibuthathaka | Ukukhanya Okubonakalayo |
| Into yoVavanyo | Iinkcukacha |
| Inkangeleko | Umgubo omhlophe ukuya kotyheli |
| Ubumsulwa (ngokwe-HPLC, %indawo) | ≥90.0% |
| Umthamo wamanzi (ngokwe-KF) | Xela ulwazi |
Iphakheji:Ibhotile, ibhegi yefoyile ye-aluminium, i-25kg/iDrum yekhadibhodi, okanye ngokweemfuno zomthengi.
Imeko Yokugcina:Gcina ivalwe ngokuqinileyo kwindawo emnyama engaphantsi kwe -15℃.
I-NADPH yi-phosphorylated derivative kwindawo ye-2' yenkqubo yeribose ring edibene ne-adenine kwi-nicotinamide adenine dinucleotide (NAD), ethatha inxaxheba kwiimpendulo ezininzi ze-anabolic, ezinje ngokwenziwa kwee-lipids, ii-fatty acids kunye nee-nucleotides. Kule mpendulo, i-NADPH iyadingeka njenge-arhente yokunciphisa kunye nomnikeli we-anion.
Ingasetyenziselwa ukwenziwa kwezinto ezidityanisiweyo zamayeza kunye nezinto ezikrwada, ikakhulu xa idityaniswe nee-enzymes ze-catalytic, kwaye okwangoku ifundwa kakhulu kwilebhu.
