SyncoZymes

iimveliso

I-Threonine deaminase (TDA)

Inkcazelo emfutshane:

Malunga neThreonine deaminase

I-ES-TDA (i-Threonine deaminase): iprotheni ye-pyridoxal phosphate eyenza i-deamination ye-threonine ivelise i-2-ketobutyric acid kunye ne-ammonia.I-Pyridoxal 5-phosphate iyimfuneko njenge-coenzyme kwinkqubo ye-catalytic.Kukho kuphela uhlobo lwe-1 yemveliso ye-enzyme ye-TDA (Inombolo njenge-ES-TDA) ephuhliswe yi-SyncoZymes, engasetyenziselwa ukulungisa i-2-ketobutyric acid okanye i-derivatives yayo kwi-threonine.
Uhlobo lwempendulo yeCatalytic:

I-Threonine deaminase TDA2

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyile:lchen@syncozymes.com


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi ngeMveliso:

Threonine deaminase TDA
Iienzymes Ikhowudi yeMveliso Inkcazo
Umgubo we-Enzyme ES-TDA-101 iseti ye-1 Nitrile Reductase, 50 mg nganye izinto ezi-1 * 50mg / into, okanye enye ubungakanani

 

Izinto eziluncedo:

★ Ubucacileyo besubstrate ephezulu.
★ Ukukhetha okuqinileyo kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Iimveliso ezingaphantsi kweemveliso.
★ Iimeko zokusabela ezithambileyo.
★ Ilungele indalo.

Imiyalelo yokusetyenziswa:

➢ Ngokuqhelekileyo, inkqubo yokusabela kufuneka ibandakanye i-substrate, isisombululo se-buffer, i-enzyme, i-coenzyme.
➢ I-TDA kufuneka yongezwe okokugqibela kwisixokelelwano sokusabela, emva kokuba i-pH kunye nobushushu bulungelelaniswe kwimeko yokusabela.

Imizekelo yosetyenziso:

Umzekelo 1(I-Synthesis ye-L-2-aminobutyric acid esuka kwi-threonine)(1):

I-Threonine deaminase TDA3

Ugcino:

Gcina iminyaka emi-2 ngaphantsi -20 ℃.

Ingqalelo:

Ungaze udibane neemeko ezigqithisileyo ezinje: ubushushu obuphezulu, i-pH ephezulu/ephantsi kunye noxinzelelo oluphezulu lwe-organic solvent.

IiReferensi:

1. Wang, Ying, et al.Iileta zeBiotechnology, 2018, 40, 1551-1559.


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