IGlucose dehydrogenase (GDH)
Inkcazelo emfutshane:
Malunga neGlucose dehydrogenase
I-ES-GDH (i-Glucose dehydrogenase): I-GDH ivuselela i-dehydrogenation ye-glucose ukuvelisa i-gluconic acid (lactone), kunye nokunciphisa i-NAD (P) + kwi-NAD (P) H, kunye ne-NAD (P) + njenge-electron receptor.I-GDH isoloko isetyenziselwa ukuhlaziywa kwe-coenzyme NAD (P) H kwiinkalo ze-biocatalysis kunye nezinye i-enzyme ephambili.Kukho iintlobo ze-10 zemveliso ye-enzyme ye-GDH (ES-GDH-101~ES-GDH-110) ephuhliswe yi-SyncoZymes, phakathi kwayo i-ES-GDH110 inomsebenzi ophezulu kwaye iyona GDH ekhuthazwayo.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
| Iienzymes | Ikhowudi yeMveliso | Inkcazo |
| Umgubo we-Enzyme | ES-GDH-101~ ES-GDH-109 | I-9 enzymes * 50mg / pc, okanye enye ubuninzi |
★ Ubucacileyo besubstrate ephezulu.
★ ukuguqulwa okuphezulu.
★ Iimveliso ezingaphantsi kweemveliso.
★ Iimeko zokusabela ezithambileyo.
★ Ilungele indalo.
➢ Ngokuqhelekileyo, inkqubo yokusabela kufuneka ibandakanye i-substrate, isisombululo se-buffer, i-enzyme, kunye ne-coenzyme.
➢ Ukuba i-GDH isetyenziselwa ukuvuselelwa kwe-coenzyme, i-enzyme ephambili iyimfuneko, kwaye inkqubo yokusabela kufuneka yenziwe ngokwe-enzyme ephambili.
Umzekelo 1(I-Biocatalysis synthesis ye-imine ukuya kwi-chiral amine kunye ne-imine reductase)(1):
Gcina iminyaka emi-2 ngaphantsi -20 ℃.
Ungaze udibane neemeko ezigqithisileyo ezinje: ubushushu obuphezulu, i-pH ephezulu/ephantsi kunye noxinzelelo oluphezulu lwe-organic solvent.
1. UBernhard LM, uMcLachlan J, uGröger H. Inkqubo yoPhuhliso lwe-Enantioselective Imine Reductase-Catalyzed Syntheses ye-Pharmaceutically Relevant Pyrrolidines[J].UPhando lweNkqubo yendalo kunye noPhuhliso, ngo-2022.
