SyncoZymes

iimveliso

I-Monoamine oxidase (MAO)

Inkcazelo emfutshane:

Malunga neMonoamine oxidase

I-ES-MAO (i-Monoamine oxidase): I-MAO yenza i-oxidative deamination ye-monoamines ukuvelisa i-hydrogen peroxide, i-ammonia kunye ne-aldehydes ehambelanayo.Kwinkqubo ye-catalytic, i-oksijini iyimfuneko njenge-oxidant.Kukho iintlobo ze-6 zeemveliso ze-enzyme ze-MAO (Inombolo njenge-ES-MAO-101~ES-MAO-106) ephuhliswe yi-SyncoZymes, enokusetyenziswa kwi-oxidative deamination ye-monoamine compounds.

Uhlobo lwe-Catalytic reaction:

I-Monoamine oxidase (MAO)2

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyile:lchen@syncozymes.com


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi ngeMveliso:

I-Monoamine oxidase (MAO)
Iienzymes Ikhowudi yeMveliso Inkcazo
Umgubo we-Enzyme ES-MAO-101~ ES-MAO-105 iseti ye-5 Monoamine Oxidase, 50 mg nganye 5 izinto * 50mg / into, okanye enye ubungakanani
Ikhithi yokuHlola (SynKit) ES-MAO-500 iseti ye-5 ye-Monoamine Oxidase, i-1 mg nganye yezinto ezi-5 * 1mg / into

Izinto eziluncedo:

★ Ubucacileyo besubstrate ephezulu.
★ Ukukhetha okuqinileyo kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Iimveliso ezingaphantsi kweemveliso.
★ Iimeko zokusabela kancinci..
★ Ilungele indalo.

Imiyalelo yokusetyenziswa:

➢ Ngokuqhelekileyo, inkqubo yokusabela kufuneka ibandakanye i-substrate, isisombululo se-buffer, i-enzyme, i-coenzyme, kunye nenkqubo yokuvuselela i-coenzyme.
➢ Zonke iintlobo ze-MAO ezihambelana neemeko ezahlukeneyo zokusabela kufuneka zifundwe nganye nganye.
➢ Uxinzelelo oluphezulu lweSubstrate okanye imveliso enento enokuthintela umsebenzi weES-MAO.Nangona kunjalo, isithintelo sinokukhululeka ngokongezwa kwebhetshi ye-substrate.

Imizekelo yosetyenziso:

Umzekelo 1(Biosynthesis of (1R,5S)-6,6-dimethyl-3-aza-bicyclo[3.1.0]hex-2-ene)(1):

I-Monoamine oxidase (MAO)3

Ugcino:

Gcina iminyaka emi-2 ngaphantsi -20 ℃.

Ingqalelo:

Ungaze udibane neemeko ezigqithisileyo ezinje: ubushushu obuphezulu, i-pH ephezulu/ephantsi kunye noxinzelelo oluphezulu lwe-organic solvent.

IiReferensi:

1 Tao Li, Jack Liang, Alexandre Ambrogelly et al.J. Am.Ikhem.Soc.2012, 134, 6467−6472.


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