Transaldolase (TAL)
Inkcazelo emfutshane:
Malunga Transaldolase
I-ES-TAL (i-Transaldolase): ikakhulu ibhekisela kwi-threonine transaldolases, enokubangela ukusabela kwi-beta-hydroxyphenylalanine derivatives kunye ne-threonine kunye ne-benzaldehyde derivatives.I-TAL yi-PLP exhomekeke kwi-enzyme.Kukho kuphela uhlobo lwe-1 lwemveliso ye-enzyme ye-TAL (Inombolo njenge-ES-TAL101) ephuhliswe yi-SyncoZymes, engasetyenziselwa ukuhlanganiswa kwe-β-hydroxyphenylalanine kunye ne-derivatives yayo.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
★ Ubucacileyo besubstrate ephezulu.
★ Ukukhetha okuqinileyo kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Iimveliso ezingaphantsi kweemveliso.
★ Iimeko zokusabela ezithambileyo.
★ Ilungele indalo.
➢ Ngokuqhelekileyo, inkqubo yokusabela kufuneka ibandakanye i-substrate, isisombululo se-buffer, i-enzyme, i-PLP, i-Mg2+.
➢ I-TAL kufuneka yongezwe okokugqibela kwisixokelelwano sokusabela, emva kokuba i-pH kunye nobushushu bulungelelaniswe kwimeko yokusabela.
Umzekelo 1(I-Synthesis of (2S, 3R)-p-methylsulfonyl phenylserine esuka kwi-p-methylsulfonyl benzaldehyde kunye nethreonine)(1):
Gcina iminyaka emi-2 ngaphantsi -20 ℃.
Ungaze udibane neemeko ezigqithisileyo ezinje: ubushushu obuphezulu, i-pH ephezulu/ephantsi kunye noxinzelelo oluphezulu lwe-organic solvent.
1. CN109836362B
