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I-Nucloside phosphoryalse (NP)
Malunga ne-nucleoside phosphoryalse
Kukho iintlobo ezi-3 zeemveliso ze-enzyme ze-NP (Inombolo njenge-ES-NP-101~ ES-NP-103) ephuhliswe yi-SyncoZymes.I-ES-NP-101 i-purine nucleoside phosphorylase, i-ES-NP-102 kunye ne-ES-NP-103 yi-pyrimidine nucleoside phosphorylase.I-Nucleosidephosphorylase inokubola i-nucleosides kwiziseko kunye ne-pentose phosphate.I-Nucleoside phosphorylase inokwahlulwa ibe yi-purine nucleoside phosphorylase kunye ne-pyrimidine nucleoside phosphorylase ngokokukhethwa kweziseko ze-nucleoside.I-Purine nucleoside phosphorylase inokumetabolise i-adenosine kwi-adenine, inosine kwi-hypoxanthine, i-guanosine kwi-guanine, kwaye ivelise i-ribose phosphate ngexesha elifanayo.I-Pyrimidine nucleoside phosphorylase inokumetabolisa i-uridine kwi-uracil kwaye ivelise i-ribose phosphate.
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I-imeyile:lchen@syncozymes.com
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IHydroaminase (HAM)
Malunga neHydroaminase
Kukho iintlobo ezi-2 zemveliso ye-enzyme ye-HAM (Inani njenge-ES-HAM-101~ ES-HAM-102) ephuhliswe yi-SyncoZymes.I-HAM inokwenza i-ammoniation ye-enoic acid okanye i-derivatives yayo ivelise i-chiral amino acids.I-HAM ingasetyenziselwa ukwenza i-chiral amino acids (okanye i-chiral amines) ukusuka kwi-enoic acids (okanye i-alkenes).Umnikezeli we-ammonia, njengamanzi ammonia okanye ityuwa ye-ammonium, iyimfuneko.
IHydroaminase uhlobo lokusabela olusebenzayo
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I-imeyile:lchen@syncozymes.com
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I-CALB engashukumiyo
I-CALB
I-Recombinant Lipase B esuka kwi-Candida antarctica (CALB) iveliswa ngokubiliswa ngaphantsi kwamanzi kunye ne-Pichia pastoris eguqulwe ngofuzo.
I-CALB ingasetyenziselwa kwisigaba samanzi okanye i-organic phase catalytic esterification, i-esterolysis, i-transesterification, i-ring ring polyester synthesis, i-aminolysis, i-hydrolysis ye-amides, i-acylation ye-amines kunye nokuphendula okongeziweyo.
I-CALB inokukhetha okuphezulu kwe-chiral kunye nokukhetha isikhundla, ngoko ingasetyenziselwa ngokubanzi kwi-oyile, ukutya, amayeza, izimonyo kunye namanye amashishini amachiza.
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I-imeyile:lchen@syncozymes.com
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I-NADH oxidase (NOX)
Malunga ne-NADH oxidase
I-ES-NOX (i-NADH oxidase): I-NOX yenza i-oxidation ye-NADH ukuya kwi-NAD +, kwaye yeye-oxidoreductase.Kwinkqubo ye-oxidation, i-O2 iyimfuneko njenge-oxidant, kwaye iyancipha ibe yi-H2O okanye i-H2O2.Kukho iintlobo ze-4 zeemveliso ze-enzyme ze-NOX (ES-NOX-101 ~ ES-NOX-104) eziphuhliswe yinkampani yethu, engasetyenziselwa ukuhlaziywa kwe-oxidation ye-coenzyme NAD +.
Uhlobo lwe-Catalytic reaction:
or
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I-imeyile:lchen@syncozymes.com
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Phenylalanine ammonia lyase (PAL)
Malunga nePhenylalanine ammonia lyase
I-ES-PAL: Iklasi ye-enzymes eyenza ukuchithwa ngokuthe ngqo kwe-L-phenylalanine kwi-asidi ye-transcinnamic.I-Syncozymes iphuhlise izinto ezili-10 ze-phenylalanine ammonia lyase (inombolo ye-ES-PAL-101~ES-PAL-110), enokusetyenziswa kwi-deamination okanye i-reverse reaction ye-phenylalanine kunye ne-derivatives yayo.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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IsiCatalase (CAT)
Malunga neCatalase
I-ES-CAT (i-Catalase): i-catalyzes ukubola kwe-H2O2 kwi-oksijini kunye namanzi.Ifumaneka ikakhulu kwi-mitochondria, i-endoplasmic reticulum, isibindi sesilwanyana kunye neeseli ezibomvu zegazi, ngakumbi kwisibindi ekugxininiseni okuphezulu, ukubonelela ngomsebenzi wokukhusela i-antioxidant kumzimba.Kwi-biocatalysis, isetyenziselwa kakhulu ukususa i-reaction by-product hydrogen peroxide kunye nokunciphisa inhibition kunye nokungasebenzi kwe-enzyme nge-hydrogen peroxide.Kukho kuphela uhlobo olu-1 lweemveliso ze-enzyme ze-CAT eziphuhliswe ngu-SyncoZymes (Inombolo njenge-ES-CAT).
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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I-Lysine oxidase (LO)
Malunga neLysine oxidase
I-ES-LO (i-Lysine oxidase): i-catalyzes i-oxidation ye-L-lysine kwi-6-amino-2-oxohexanoic acid (okanye i-lactone yayo).Kukho kuphela uhlobo olu-1 lwemveliso ye-enzyme ye-LO (Inani njenge-ES-LO) ephuhliswe ngu-SyncoZymes.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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Phosphokinase (PKase)
Malunga nePhosphokinase
I-ES-PKase (i-Phosphokinase): ibangela ukuhanjiswa kwamaqela e-phosphate kwi-ATP kwezinye iikhompawundi.Ikwadala ukudluliselwa kwamaqela ephosphate kwezinye iinucleosides zetriphosphate ngamanye amaxesha.Uninzi lwe-kinases ludinga i-ion zetsimbi ze-divalent ukuba zithathe inxaxheba ekuphenduleni (ngokubanzi i-Mg2 +).Kukho iintlobo ze-21 zeemveliso ze-enzyme ze-PCase (Inombolo njenge-ES-PKase101~ ES-PKase-121) ephuhliswe yi-SyncoZymes.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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Cyclooxygenase (COX)
Malunga neCyclooxygenase
I-ES-COX (i-Cyclooxygenase): ibangela ukuguqulwa kweebhondi ze-C = C kwi-epoxide.Kukho iintlobo ezili-11 zeemveliso ze-enzyme ze-COX (Inombolo njenge-ES-COX101~ ES-COX-111) ephuhliswe yi-SyncoZymes.Ngokweendlela ezahlukeneyo ze-catalytic, i-COX ye-SyncoZymes yahlulwe yaba yi-haloperoxidase kunye ne-styrene monooxygenase.I-ES-COX101, i-102, i-107-111 ye-haloperoxidase, ngelixa i-ES-COX103-106 yeye-styrene monooxygenase.
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I-imeyile:lchen@syncozymes.com
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I-Cyclohexanone monooxygenase (CHMO)
Malunga neCyclohexanone monooxygenase
I-ES-CHMO (i-Cyclohexanone monooxygenase): i-Baeyer Villiger monooxygenase (BVMO) kunye ne-cyclohexanone njenge-substrate, i-oxidize i-cyclohexanone kwi-cyclohexanol isebenzisa i-oxygen.
Luhlobo lwe-enzyme exhomekeke kwi-flavin.I-flavin ene-oxidized iyancitshiswa ibe yi-flavin ngomjikelezo wokunciphisa i-coenzyme II (NADPH) kwi-oxidation elandelayo.Ke ngoko, i-cofactor NADPH iyimfuneko kumjikelo weflavin.Kukho kuphela uhlobo lwe-1 lwemveliso ye-enzyme ye-CHMO (Inombolo njenge-ES-CHMO101) ephuhliswe yi-SyncoZymes, engasetyenziselwa i-oxidize i-cyclohexanone kwi-cyclohexanone.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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I-Carboxylic acid reductase (CAR)
Malunga neCarboxylic acid reductase
I-ES-CAR (i-Carboxylic acid reductase): ibangela ukunciphisa iqela le-carboxyl kwiqela le-aldehyde.Kwinkqubo ye-catalytic, ukusebenza kwe-ATP kunye ne-coenzyme NADPH iyafuneka njengabathuthi be-hydrogen.Kukho iintlobo ezi-2 zeemveliso ze-enzyme ze-CAR (Inombolo njenge-ES-CAR101 ~ ES-CAR-102) ephuhliswe yi-SyncoZymes.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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Transaldolase (TAL)
Malunga Transaldolase
I-ES-TAL (i-Transaldolase): ikakhulu ibhekisela kwi-threonine transaldolases, enokubangela ukusabela kwi-beta-hydroxyphenylalanine derivatives kunye ne-threonine kunye ne-benzaldehyde derivatives.I-TAL yi-PLP exhomekeke kwi-enzyme.Kukho kuphela uhlobo lwe-1 lwemveliso ye-enzyme ye-TAL (Inombolo njenge-ES-TAL101) ephuhliswe yi-SyncoZymes, engasetyenziselwa ukuhlanganiswa kwe-β-hydroxyphenylalanine kunye ne-derivatives yayo.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
