I-glucose dehydrogenase (GDH)
Inkcazo emfutshane:
Malunga neGlucose dehydrogenase
I-ES-GDH (i-glucose dehydrogenase): I-GDH ivuselela ukususwa kwe-glucose ukuze ivelise i-gluconic acid (i-lactone), kwaye inciphise i-NAD(P)+ ibe yi-NAD(P)H, kunye ne-NAD(P)+ njenge-electron receptor. I-GDH idla ngokusetyenziselwa ukuvuselelwa kwe-coenzyme NAD(P)H kwiindawo ze-biocatalysis kunye nezinye ii-enzyme eziphambili. Kukho iintlobo ezili-10 zeemveliso ze-enzyme ze-GDH (ES-GDH-101~ES-GDH-110) ezenziwe yiSyncoZymes, phakathi kwazo i-ES-GDH110 inomsebenzi ophezulu kwaye yeyona GDH icetyiswayo kakhulu.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
| Iienzymes | Ikhowudi yeMveliso | Inkcazo |
| Umgubo we-Enzyme | ES-GDH-101~ ES-GDH-109 | Iienzymes ezi-9 * 50mg/pc, okanye olunye ubuninzi |
★ Ukucaciswa okuphezulu kwe-substrate.
★ Uguquko oluphezulu.
★ Iimveliso ezingaphantsi kwezinye.
★ Iimeko zokusabela okuncinci.
★ Inobuhlobo nokusingqongileyo.
➢ Ngokwesiqhelo, inkqubo yokusabela kufuneka iquke i-substrate, isisombululo se-buffer, i-enzyme, kunye ne-coenzyme.
➢ Ukuba i-GDH isetyenziselwa ukuvuselelwa kwe-coenzyme, i-enzyme ephambili iyimfuneko, kwaye inkqubo yokusabela kufuneka yenziwe ngokwe-enzyme ephambili.
Umzekelo 1 (Ukwenziwa kwe-biocatalysis ye-imine ukuya kwi-chiral amine kunye ne-imine reductase)(1):
Gcina iminyaka emibini ngaphantsi kwe -20℃.
Ungaze udibane neemeko ezinzima ezifana nobushushu obuphezulu, i-pH ephezulu/ephantsi kunye nesinyibilikisi sendalo esinoxinzelelo oluphezulu.
1. UBernhard LM, uMcLachlan J, uGröger H. Uphuhliso lweNkqubo ye-Enantioselective Imine Reductase-Catalyzed Syntheses ye-Pharmaceutical Relevant Pyrrolidines [J]. Uphando noPhuhliso lweNkqubo ye-Organic, 2022.
