Umfanekiso oFakiweyo we-Oxynitrilases (HNL)

IiOxynitrilases (HNL)

Inkcazo emfutshane:

Malunga ne-oxynitrilases

Ii-ES-HNL: Yi-enzyme yodidi ekhetha ukongezwa kwe-HCN kwi-aldehydes (ii-ketones) ukuze kufunyanwe i-R okanye i-S type cyanide alcohols, enokuguqulwa ngokulula ibe ziintlobo ezininzi zamayeza okanye iziyobisi ngokusebenzisa indlela yeekhemikhali.
Kukho iintlobo ezingama-29 zeemveliso ze-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) eziphuhliswe yiSyncoZymes. I-SZ-HNL sisixhobo esiluncedo sokudibanisa i-(R)-cyanohydrins okanye (S)-cyanohydrins ngokweengingqi kunye nokukhetha i-stereo-selective kwiindidi ezahlukeneyo ze-aldehydes ezinuka kamnandi, i-aliphatic kunye ne-heterocyclic okanye ii-ketones.
Uhlobo lwempendulo ye-Catalytic:

Ii-Oxynitrilases HNL2

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I-imeyile:lchen@syncozymes.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi lweMveliso:

Iienzymes	Ikhowudi yeMveliso	Inkcazo
Umgubo we-Enzyme	ES-HNL-101~ ES-HNL-129	iseti yee-oxynitrilases ezingama-29, i-50 mg nganye, izinto ezingama-29 * 50mg / into, okanye olunye ubungakanani
Isixhobo sokuvavanya (iSynKit)	I-ES-HNL-1800	iseti ye-18 (S)-oxynitrilases, 1 mg nganye Izinto ezili-18 * 1mg / into
Isixhobo sokuvavanya (iSynKit)	I-ES-HNL-1100	iseti yee-11 (R)-oxynitrilases, 1 mg nganye 11izinto * 1mg / into

Iingenelo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okunamandla kwe-chiral.
★ Uguquko oluphezulu.
★ Iimveliso ezingaphantsi kwezinye.
★ Iimeko zokusabela okuncinci.
★ Inobuhlobo nokusingqongileyo.

Imiyalelo yokusebenzisa:

➢ Ngokwesiqhelo, inkqubo yokusabela kufuneka iquke i-substrate (i-aldehydes / ii-ketones, i-HCN), isisombululo se-buffer (i-pH yempendulo efanelekileyo) kunye nee-enzymes.
➢ Zonke ii-ES-HNL zingavavanywa ngokulandelelana kwinkqubo yokusabela engentla okanye nge-HNL Screening Kit (SynKit HNL).
➢ Zonke iintlobo ze-ES-HNLs ezihambelana neemeko ezahlukeneyo zokusabela ezifanelekileyo kufuneka zifundwe nganye nganye.
➢ I-substrate enoxinzelelo oluphezulu okanye imveliso enoxinzelelo oluphezulu inokuthintela umsebenzi we-ES-HNL. Nangona kunjalo, uthintelo lunokupheliswa ngokongeza i-substrate ngebhetshi.