IiOxynitrilases (HNL)

Inkcazelo emfutshane:

Malunga ne-oxynitrilases

I-ES-HNLs: I-enzyme yeklasi eyenza i-enantioselectively i-catalyze ukongezwa kwe-HCN kwi-aldehydes (i-ketones) ukufumana i-R okanye i-S yohlobo lwe-cyanide alcohols, enokuguqulwa ngokulula kwiindidi ezininzi zeziyobisi okanye izibilini zeziyobisi ngokusebenzisa indlela yekhemikhali.
Kukho iintlobo ze-29 zeemveliso ze-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) ephuhliswe ngu-SyncoZymes.I-SZ-HNL sisixhobo esiluncedo kwi-regio- kunye ne-stereo- selective synthesis ye (R) -cyanohydrins okanye (S) -cyanohydrins evela kwiindidi ze-aldehydes ezivumba, i-aliphatic kunye ne-heterocyclic okanye i-ketones.
Uhlobo lwe-Catalytic reaction:

Oxynitrilases HNL2

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyile:lchen@syncozymes.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi ngeMveliso:

Iienzymes	Ikhowudi yeMveliso	Inkcazo
Umgubo we-Enzyme	ES-HNL-101~ ES-HNL-129	iseti ye-29 oxynitrilases, 50 mg nganye 29 izinto * 50mg / into, okanye enye ubungakanani
Ikhithi yokuHlola (SynKit)	ES-HNL-1800	iseti ye-18 (S) -oxynitrilases, 1 mg nganye 18 izinto * 1mg / into
Ikhithi yokuHlola (SynKit)	ES-HNL-1100	iseti ye-11 (R) -oxynitrilases, 1 mg nganye 11items * 1mg / into

Izinto eziluncedo:

★ Ubucacileyo besubstrate ephezulu.
★ Ukukhetha okuqinileyo kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Iimveliso ezingaphantsi kweemveliso.
★ Iimeko zokusabela ezithambileyo.
★ Ilungele indalo.

Imiyalelo yokusetyenziswa:

➢ Ngokuqhelekileyo, inkqubo yokusabela kufuneka ibandakanye i-substrate (aldehydes / ketones, HCN), isisombululo se-buffer (optimum reaction pH) kunye nee-enzymes.
➢ Zonke ii-ES-HNLs zinokuvavanywa ngokulandelelanayo kwi-reaction system engentla okanye nge-HNL Screening Kit (SynKit HNL).
➢ Zonke iintlobo zee-ES-HNL ezingqamene neemeko ezahlukeneyo zokusabela kufuneka zifundwe zodwa.
➢ Uxinzelelo oluphezulu lweSubstrate okanye imveliso enayo inokuthintela ukusebenza kweES-HNL.Nangona kunjalo, isithintelo sinokukhululeka ngokongezwa kwebhetshi ye-substrate.