Umfanekiso obonisiweyo wePhenylalanine dehydrogenase (PDH)

I-Phenylalanine dehydrogenase (PDH)

Inkcazo emfutshane:

Malunga nePhenylalanine dehydrogenase

I-ES-PDH: Udidi lwe-oxidoreductase. Impendulo entle inokwenza i-oxidative deamination yetyuwa ye-L phenylalanine xa kukho i-NAD ukuvelisa ityuwa ye-phenylpyruvate, kwaye impendulo echaseneyo ingenza i-synthesis yetyuwa ye-amino acid ehambelanayo kwityuwa ye-phenylpyruvate. I-Syncozymes iphuhlise izinto ezi-8 ze-phenylalanine dehydrogenase (ezibhalwe ngenombolo ye-ES-PDH-101~ES-PDH-108). I-ES-PDH ingasetyenziselwa ukulungisa ityuwa ye-phenylalanine okanye ityuwa ye-amino acid ehambelanayo kwityuwa ye-phenylpyruvic acid okanye izinto eziphuma kuyo.
Uhlobo lwempendulo ye-Catalytic:

I-PDH2

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I-imeyile:lchen@syncozymes.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi lweMveliso:

Iienzymes	Ikhowudi yeMveliso	Inkcazo
Umgubo we-Enzyme	ES-PDH-101~ ES-PDH-108	iseti ye-8 Nitrile Reductase, 50 mg nganye 8 izinto * 50mg / into, okanye olunye ubungakanani

Iingenelo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okunamandla kwe-chiral.
★ Uguquko oluphezulu.
★ Iimveliso ezingaphantsi kwezinye.
★ Iimeko zokusabela okuncinci.
★ Inobuhlobo nokusingqongileyo.

Imiyalelo yokusebenzisa:

➢ Ngokwesiqhelo, inkqubo yokusabela kufuneka iquke i-substrate, isisombululo se-buffer, i-enzyme, i-coenzyme (NAD(H)), inkqubo yokuvuselela i-coenzyme (umz. i-ammonium formate kunye ne-formate dehydrogenase).
➢ Uhlobo ngalunye lwe-ES-PDH luhambelana neemeko ezahlukeneyo zokusabela ezifanelekileyo, ezinokufundwa nganye nganye ukuba kuyimfuneko.
➢ I-ES-PDH kufuneka yongezwe okokugqibela kwinkqubo yokusabela ukuze kugcinwe umsebenzi.