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I-Ketoreductase (KRED)
Malunga neKetoreductase
Ii-Enzymes: Ngaba zii-macromolecular biological catalysts, uninzi lwee-enzymes ziiproteni.
I-Ketoreductase: Ekwabizwa ngokuba “yiCarbonyl reductase”, zii-enzymes ezenza ukuba i-redox ibuye umva phakathi kwe-aldehydes / ii-ketones kunye ne-alcohol, kwaye idinga ii-coenzymes njenge-H transmitter njenge-NADH okanye i-NADPH.Kukho iindidi ezintathu eziphambili ze-KRED: I-Dehydrogenase ye-Short-chain / Reductases (SDRs), i-Medium-chain Dehydrogenases / Reductases (MDRs), kunye ne-Aldo-KetoReductases (AKRs).Imisebenzi ye-catalytic ye-3 iyafana, kodwa isakhiwo kunye neempawu zahluke kakhulu.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Transaminase (ATA)
Malunga ne-transaminase
I-ATA esuka kwi-SyncoZymes: Kukho iintlobo ze-66 zeemveliso ze-enzyme ze-ATA (Inombolo njenge-ES-ATA-101~ES-ATA-166) ephuhliswe ngu-SyncoZymes.I-SZ-ATA sisixhobo esiluncedo sokwenza i-regio- kunye ne-stereoelective synthesis ye-chiral amines, i-amino acids kunye ne-derivatives yazo ezivela kwiindidi ze-aliphatic kunye ne-aromatic ketoacids, i-aldehydes, i-ketones kunye ne-ketose.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitrilase (NIT)
Malunga neNitrilase
I-ES-NITs: Ukuguqula ngokuthe ngqo iqela le-cyanide kwiqela le-carboxyl, ukulungiselela i-carboxylic acid, esetyenziswa ngokubanzi kumayeza, ukukhuselwa kwendalo, ishishini lemichiza, ukongezwa kokutya, i-textile, imveliso yezolimo kunye nezinye iinkalo.
Kukho iintlobo ze-40 zeemveliso ze-Nitrilase (NIT) (Inombolo njenge-ES-NIT-101~ES-NIT-140) ephuhliswe yi-SyncoZymes.I-ES-NIT sisixhobo esiluncedo ekwenzeni i-chiral carboxylic acids ngokusebenzisa i-regio- kunye ne-stereoselective hydrolysis yoluhlu olubanzi lwe-aliphatic kunye ne-aromatics nitriles.Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitrile hydratase (NHT)
Malunga ne-ES-NHTs
I-ES-NHTs: iklasi ye-metalloenzyme, ekhetha i-hydrate nitriles kwi-amide ephambili ehambelanayo.Asetyenziswa ngokubanzi kungekuphela nje ukuhlanganiswa kwe-amino acids, i-amides, i-carboxylic acid kunye ne-derivatives yazo, kodwa kunye nokulungiselela iziyobisi ze-chiral.Kukho iindidi ezingama-24 ze-nitrile hydratases eziphuhliswe yi-SyncoZymes (Inombolo njenge-ES-NHT-101～ES-NHT-124).
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Amidase (AMD)
I-AMD esuka kwi-SyncoZymes: Kukho iintlobo ezili-19 zeemveliso ze-enzyme ye-AMD (Inani njenge-ES-AMD-101~ES-AMD-119) ephuhliswe yi-SyncoZymes.I-SZ-AMD sisixhobo esiluncedo sokwenza i-regio- kunye ne-stereoelective synthesis ye-chiral carboxylic acid kunye nezinto eziphuma kuzo kwiindidi ze-aliphatic kunye ne-aromatic amides.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Ene reductase (ERED)
Malunga ne-ene reductase
I-ES-EREDs: Ivela kwintsapho ye-enzymes endala ephuzi ekhetha ukunciphisa i-C = C kwi-α, i-β -i-unsaturated compounds kunye namaqela athatha i-electron.Zisetyenziswa ngokubanzi kuphononongo lwe-amino acid derivatives, izinto eziphilayo, i-pharmaceutical intermediates, iziqholo kunye neebhloko ze-chiral.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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IiOxynitrilases (HNL)
Malunga ne-oxynitrilases
I-ES-HNLs: I-enzyme yeklasi eyenza i-enantioselectively i-catalyze ukongezwa kwe-HCN kwi-aldehydes (i-ketones) ukufumana i-R okanye i-S yohlobo lwe-cyanide alcohols, enokuguqulwa ngokulula kwiindidi ezininzi zeziyobisi okanye izibilini zeziyobisi ngokusebenzisa indlela yekhemikhali.
Kukho iintlobo ze-29 zeemveliso ze-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) ephuhliswe ngu-SyncoZymes.I-SZ-HNL sisixhobo esiluncedo kwi-regio- kunye ne-stereo- selective synthesis ye (R) -cyanohydrins okanye (S) -cyanohydrins evela kwiindidi ze-aldehydes ezivumba, i-aliphatic kunye ne-heterocyclic okanye i-ketones.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitro reductase (NTR)
Malunga ne-nitro reductase
I-ES-NTRs: Ngaba i-flavoenzymes eyenza ukunciphisa i-NAD (P) H-exhomekeke kumaqela e-nitro kwiikhompawundi ze-nitroaromatic kunye ne-nitroheterocyclic kwi-hydroxylamino kunye / okanye i-amino derivatives.Zisetyenziswa ngokubanzi kwi-organic synthesis ye-hydroxylamine enevumba elimnandi kunye ne-amine enuka kamnandi, unyango lwethumba, ubhaqo lwebhayoloji kunye nokuthotywa kwezinto ezingcolisa indalo.Kukho iintlobo ezili-12 zeemveliso ze-Nitro reductase (NTR) (Inombolo njenge-ES-NTR-101~ES-NTR-112) ephuhliswe ngu-SyncoZymes.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Aldolase (DERA)
I-ES-DERAs: Inokwenza ngokufanelekileyo ukongezwa kwe-stereoelective yee-ketones zabaxhasi kwi-receptor aldehydes.Ngaphezu koko, ukusabela kunokwenziwa kwisisombululo esimanzi se-pH engathathi hlangothi ngaphandle kwamanyathelo okukhusela akhethekileyo.Bangabeklasi I aldolase, eyenza isiseko sikaShiff kwinkqubo ye-catalytic.I-substrate ihlanganiswe ngokubambisana kunye neqela le-amino lendawo esebenzayo ukuqalisa ukuphuka kunye nokwakhiwa kwebhondi.Umahluko phakathi kwe-DERAs kunye nezinye ii-aldolases kukuba ii-substrates ezizenza zi-aldehydes kwaye zinokungena kwi-aldehydes condensation eqhubekayo.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Cytochrome P450 monooxygenase (CYP)
Malunga neCYP
I-ES-CYPs: Iklasi ye-redox enzymes kunye ne-mercaptan-heme njengeziko elisebenzayo lokunyusa ukuhanjiswa kwe-oxygen.Ziyi-oxygen e-terminal kwaye idinga i-heme ukuze isebenze i-oxygen.
I-Cytochrome P450 monooxygenase yenza i-oxidation, i-epoxidation kunye ne-hydroxylation ye-alkyl, i-hydroxylation kunye ne-oxidation ye-ammonia, i-oxidation yesulfure, i-dealkylation (i-oxygen, i-sulfur, i-ammonia), i-oxidative dehydrogenation, i-deamination kunye ne-dehalogenation.
Kukho iintlobo ezisi-8 zeemveliso ze-cytochrome P450 monooxygenase (Inombolo njenge-ES-CYP-101～ES-CYP-108) ephuhliswe ngu-SyncoZymes.Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Alcohol oxidase (AOX)
Malunga ne-alcohol oxidase
I-ES-AOXs: Ezi enzymes ziyakwazi ukwenza i-oxidation yee-alcohols ezinamafutha okanye i-aryl-alcohols ukwenza i-aldehydes.Basebenzisa ioksijini yemolekyuli kodwa ayifuni icofactor eyongeziweyo ngaphandle, kunye nehydrogen peroxide iveliswa.
Kukho iintlobo ezi-6 zeemveliso ze-alcohol oxidases (Inani njenge-ES-AOX-101~ES-AOX-106) ephuhliswe yi-SyncoZymes.I-ES-AOX101 kunye ne-ES-AOX102 zikhetha i-aliphatic alcohol substrates, i-ES-AOX103~ ES-AOX105 ikhetha i-alcohol substrates enuka kamnandi, kwaye i-ES-AOX106 yi-cholesterol oxidase.I-SZ-AOX sisixhobo esiluncedo sokwenza i-oxidation yee-alcohols ezinamafutha okanye i-aryl-alcohols ukuvelisa i-aldehydes.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-D-Amino acid dehydrogenase (D-AADH)
Malunga ne-D-Amino acid dehydrogenase
I-ES-D-AADH (i-D-Amino acid dehydrogenase): i-enzyme enokunciphisa i-2-keto acid kwi-D-amino acid ehambelanayo.Ukusabela kufuna i-NADP (H) kunye nomxhasi we-ammonia we-inorganic (njenge-ammonia okanye i-ammonium ion).Kukho iintlobo ze-17 ze-D-amino acid dehydrogenases (Inombolo njenge-ES-DAADH-101~ ES-DAADH-117) ephuhliswe yi-SyncoZymes.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
