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I-Transaldolase (TAL)
Malunga neTransaldolase
I-ES-TAL (iTransaldolase): ibhekisa ikakhulu kwi-threonine transaldolases, enokuthi ibangele ukusabela ekuhlanganiseni i-β-hydroxyphenylalanine derivatives kunye ne-threonine kunye ne-benzaldehyde derivatives. I-TAL yi-enzyme exhomekeke kwi-PLP. Kukho uhlobo olunye kuphela lwemveliso ye-TAL enzyme (iNombolo njenge-ES-TAL101) eyenziwe yiSyncoZymes, enokusetyenziswa ekuhlanganiseni i-β-hydroxyphenylalanine kunye ne-derivatives yayo.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Ketoreductase (KRED)
Malunga neKetoreductase
Iienzyme: Zii-macromolecular biological catalysts, uninzi lwee-enzyme ziiproteni.
I-Ketoreductase: Ikwabizwa ngokuba yi-“Carbonyl reductase”, zii-enzymes ezivuselela i-reversible redox reaction phakathi kwe-aldehydes/ketones kunye ne-alcohols, kwaye zifuna ii-coenzymes njenge-H transmitter ezifana ne-NADH okanye i-NADPH. Kukho iindidi ezintathu eziphambili ze-KRED: I-Short-chain Dehydrogenase / Reductases (SDRs), i-Medium-chain Dehydrogenases / Reductases (MDRs), kunye ne-Aldo-KetoReductases (AKRs). Imisebenzi ye-catalytic yala mathathu iyafana, kodwa ulwakhiwo kunye neempawu zahlukile kakhulu.
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Transaminase (ATA)
Malunga ne-transaminase
I-ATA evela kwiSyncoZymes: Kukho iintlobo ezingama-66 zeemveliso ze-enzyme ze-ATA (Inombolo njenge-ES-ATA-101~ES-ATA-166) eziphuhliswe yiSyncoZymes. I-SZ-ATA sisixhobo esiluncedo sokuvuselela ukwenziwa kwe-regio- kunye ne-stereoselective ye-chiral amines, ii-amino acids kunye ne-derivatives yazo ezivela kwiindidi ezahlukeneyo ze-aliphatic kunye ne-aromatic ketoacids, i-aldehydes, ii-ketones kunye nee-ketoses.
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitrilase (i-NIT)
Malunga neNitrilase
Ii-ES-NIT: Guqula iqela le-cyanide ngqo libe liqela le-carboxyl, ukulungiselela i-carboxylic acid, esetyenziswa kakhulu kwezonyango, ukhuseleko lokusingqongileyo, kushishino lweekhemikhali, kwizithako zokutya, kwimpahla yelaphu, kwimveliso yezolimo nakwezinye iindawo.
Kukho iintlobo ezingama-40 zeemveliso zeNitrilase (NIT) (Inombolo njenge-ES-NIT-101~ES-NIT-140) eziphuhliswe yiSyncoZymes. I-ES-NIT sisixhobo esiluncedo sokuvuselela ukwenziwa kwee-chiral carboxylic acids ngokusebenzisa i-regio- kunye ne-stereoselective hydrolysis yoluhlu olubanzi lwee-aliphatic kunye nee-aromatic nitriles.Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitrile hydratase (NHT)
Malunga ne-ES-NHTs
Ii-ES-NHTs: udidi lwe-metalloenzyme, olukhetha ukufunxa ii-nitriles kwi-primary amide ehambelanayo. Zisetyenziswa kakhulu kungekuphela nje ekuhlanganiseni ii-amino acids, ii-amides, ii-carboxylic acids kunye ne-derivatives zazo, kodwa nasekulungiseleleni amayeza e-chiral. Kukho iintlobo ezingama-24 ze-nitrile hydratases eziphuhliswe yiSyncoZymes (Inombolo njenge-ES-NHT-101～ES-NHT-124).
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Amidase (AMD)
I-AMD evela kwiSyncoZymes: Kukho iintlobo ezili-19 zeemveliso ze-enzyme ze-AMD (Inombolo njenge-ES-AMD-101~ES-AMD-119) eziphuhliswe yiSyncoZymes. I-SZ-AMD sisixhobo esiluncedo sokuvuselela ukwenziwa kwe-regio- kunye ne-stereoselective ye-chiral carboxylic acids kunye ne-derivatives yazo ezivela kwiindidi ezahlukeneyo ze-aliphatic kunye ne-aromatic amides.
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Ene reductase (ERED)
Malunga ne-ene reductase
Ii-ES-ERED: Ziyinxalenye yosapho lwee-enzymes ezindala ezityheli ezinciphisa ngokukhetha i-C=C kwiikhompawundi ze-α, β-unsaturated ezinamaqela afunxa ii-electron. Zisetyenziswa kakhulu kuphononongo lwee-amino acid derivatives, izinto eziphilayo, izinto ezidityanisiweyo zamayeza, iziqholo kunye neebhloko ze-chiral.
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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IiOxynitrilases (HNL)
Malunga ne-oxynitrilases
Ii-ES-HNL: Yi-enzyme yodidi ekhetha ukongezwa kwe-HCN kwi-aldehydes (ii-ketones) ukuze kufunyanwe i-R okanye i-S type cyanide alcohols, enokuguqulwa ngokulula ibe ziintlobo ezininzi zamayeza okanye iziyobisi ngokusebenzisa indlela yeekhemikhali.
Kukho iintlobo ezingama-29 zeemveliso ze-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) eziphuhliswe yiSyncoZymes. I-SZ-HNL sisixhobo esiluncedo sokudibanisa i-(R)-cyanohydrins okanye (S)-cyanohydrins ngokweengingqi kunye nokukhetha i-stereo-selective kwiindidi ezahlukeneyo ze-aldehydes ezinuka kamnandi, i-aliphatic kunye ne-heterocyclic okanye ii-ketones.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitro reductase (NTR)
Malunga ne-nitro reductase
Ii-ES-NTR: Zii-flavoenzymes ezibangela ukunciphisa amaqela e-nitro ngokuxhomekeke kwi-NAD(P)H kwiikhompawundi ze-nitroaromatic kunye ne-nitroheterocyclic ukuya kwi-hydroxylamino kunye/okanye i-amino derivatives. Zisetyenziswa kakhulu kwi-organic synthesis ye-aromatic hydroxylamine kunye ne-aromatic amine, unyango lwe-tumor, ukufunyanwa kwezinto eziphilayo kunye nokuwohloka kokungcola kwendalo. Kukho iintlobo ezili-12 zeemveliso zeNitro reductase (NTR) (Inombolo njenge-ES-NTR-101~ES-NTR-112) ezenziwe yiSyncoZymes.
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Aldolase (i-DERA)
I-ES-DERA: Ingavuselela ngempumelelo ukongezwa kwee-ketones ze-donor kwi-receptor aldehydes. Ngaphezu koko, impendulo ingenziwa kwisisombululo samanzi se-pH engathathi hlangothi ngaphandle kwamanyathelo akhethekileyo okukhusela. Zikwi-aldolase yeklasi I, eyenza isiseko seShiff kwinkqubo ye-catalytic. I-substrate idityaniswe ngokudibeneyo neqela le-amino lendawo esebenzayo ukuqala ukwaphuka nokwakheka kwe-bond. Umahluko phakathi kwe-DERAs kunye nezinye i-aldolases kukuba i-substrates abazivuselelayo zi-aldehydes kwaye zinokuqhubeka nokufuma kwe-aldehydes.
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I-imeyile:lchen@syncozymes.com
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I-cytochrome P450 monooxygenase (CYP)
Malunga ne-CYP
I-ES-CYPs: Ludidi lwee-enzymes ze-redox ezine-mercaptan-heme njengeziko elisebenzayo lokuguqula ukuhanjiswa kweoksijini. Zii-oxygenases zesiphelo kwaye zifuna i-heme ukuze isebenze ioksijini.
I-Cytochrome P450 monooxygenase ivuselela i-oxidation, i-epoxidation kunye ne-hydroxylation ye-alkyl, i-hydroxylation kunye ne-oxidation ye-ammonia, i-oxidation ye-sulfur, i-dealkylation (i-oxygen, i-sulfur, i-ammonia), i-oxidative dehydrogenation, i-deamination kunye ne-dehalogenation.
Kukho iintlobo ezisi-8 zeemveliso ze-cytochrome P450 monooxygenase (Inombolo njenge-ES-CYP-101～ES-CYP-108) ezenziwe yiSyncoZymes.Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-oxidase yotywala (AOX)
Malunga ne-oxidase yotywala
Ii-ES-AOX: Ezi enzymes ziyakwazi ukushukumisa i-oxidation ye-fatty alcohols okanye i-aryl-alcohols ukuze zenze i-aldehydes. Zisebenzisa i-molecule oxygen kodwa azifuni i-cofactor eyongeziweyo ngaphandle, kunye ne-hydrogen peroxide eveliswayo.
Kukho iintlobo ezi-6 zeemveliso ze-alcohol oxidases (Inombolo njenge-ES-AOX-101~ES-AOX-106) eziphuhliswe yiSyncoZymes. I-ES-AOX101 kunye ne-ES-AOX102 zikhetha ii-substrates ze-aliphatic alcohol, i-ES-AOX103~ ES-AOX105 zikhetha ii-substrates ze-alcohol ezinuka kamnandi, kwaye i-ES-AOX106 yi-cholesterol oxidase. I-SZ-AOX sisixhobo esiluncedo sokubangela i-oxidation yee-fatty alcohols okanye ii-aryl-alcohols ukuvelisa i-aldehydes.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
