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I-Esterase&Lipase (PLE&CALB)
Malunga ne-Esterase&Lipase
I-ES-PLEs: Iklasi ye-hydrolases eyenza ukubunjwa kunye nokuphulwa kweebhondi ze-ester.Banokuthatha inxaxheba kwiindidi ezininzi ze-biochemical reactions, ezifana ne-esterification, i-transesterification kunye ne-hydrolysis.Zisetyenziswa ngokubanzi kwiinkalo ezininzi ezifana nokulungiswa kokutya, ishishini lemichiza, i-biomedicine, amayeza e-chiral kunye nonyango lokusingqongileyo.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Epoxide hydrolase (EH)
Malunga ne-epoxide hydrolase
I-EH yi-ether hydrolase eyenza i-stereoelective hydrolysis ye-racemic epoxides ukuvelisa i-1, i-2-diol kunye ne-optical active epoxides, engasetyenziselwa ukulungiswa kwe-chiral ye-epoxides okanye ukulungiswa kwe-chiral diols.Zisetyenziswa kakhulu kwezamayeza nakwezinye iindawo.Kukho iintlobo ezi-3 zeemveliso ze-epoxide hydrolases (Inani njenge-ES-EH-101～ES-EH-103) ephuhliswe yi-SyncoZymes.I-ES-EH sisixhobo esiluncedo sokwenza i-synthesis ye-chiral alcohols ngokusebenzisa i-stereoselective hydrolysis ye-aliphatic kunye ne-aromatic epoxides.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Malunga neFomate dehydrogenase
I-ES-FDH (i-Formate dehydrogenase): I-FDH yenza i-dehydrogenation ye-ammonium formate ukuvelisa i-carbon dioxide kunye ne-ammonia, kunye nokunciphisa i-NAD kwi-NADH kunye ne-NAD njenge-electron receptor.I-FDH isoloko isetyenziselwa ukuhlaziywa kwe-coenzyme NADH.Kukho iintlobo ezi-4 zeemveliso ze-enzyme ze-FDH (ES-FDH-101~ES-FDH-104) eziphuhliswe yi-SyncoZymes, phakathi kwazo i-ES-FDH102 inomsebenzi ophezulu kwaye yeyona FDH ecetyiswayo.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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IGlucose dehydrogenase (GDH)
Malunga neGlucose dehydrogenase
I-ES-GDH (i-Glucose dehydrogenase): I-GDH ivuselela i-dehydrogenation ye-glucose ukuvelisa i-gluconic acid (lactone), kunye nokunciphisa i-NAD (P) + kwi-NAD (P) H, kunye ne-NAD (P) + njenge-electron receptor.I-GDH isoloko isetyenziselwa ukuhlaziywa kwe-coenzyme NAD (P) H kwiinkalo ze-biocatalysis kunye nezinye i-enzyme ephambili.Kukho iintlobo ze-10 zemveliso ye-enzyme ye-GDH (ES-GDH-101~ES-GDH-110) ephuhliswe yi-SyncoZymes, phakathi kwayo i-ES-GDH110 inomsebenzi ophezulu kwaye iyona GDH ekhuthazwayo.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Monoamine oxidase (MAO)
Malunga neMonoamine oxidase
I-ES-MAO (i-Monoamine oxidase): I-MAO yenza i-oxidative deamination ye-monoamines ukuvelisa i-hydrogen peroxide, i-ammonia kunye ne-aldehydes ehambelanayo.Kwinkqubo ye-catalytic, i-oksijini iyimfuneko njenge-oxidant.Kukho iintlobo ze-6 zeemveliso ze-enzyme ze-MAO (Inombolo njenge-ES-MAO-101～ES-MAO-106) ephuhliswe yi-SyncoZymes, enokusetyenziswa kwi-oxidative deamination ye-monoamine compounds.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Lactate Dehydrogenase (LDH)
Malunga neLactate dehydrogenase
Kukho uhlobo lwe-1 lwemveliso ye-enzyme ye-LDH (Inombolo njenge-ES-LDH) ephuhliswe yi-SyncoZymes.I-LDH inokubangela ukunciphisa i-pyruvate kwi-L-lactic acid, okanye ukunciphisa ezinye i-α-keto acids ezifanayo.Kwinkqubo ye-catalysis, i-NADH iyimfuneko njenge-hydrogen transporter.
Lactate dehydrogenasecatalytic reaction type
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Imine reductase (IRED)
Malunga noImine reductase
I-ES-IRED: Iklasi ye-enzymes eyenza ukunciphisa i-C = N ibhondi kwi-CN bond.Yeye-enzyme ye-redox, kunye ne-coenzyme NADPH yokuthutha i-hydrogen.Ngokokhetho lwe-chiral lweemveliso, zinokwahlulwa zibe yi-R-IRED kunye ne-S-IRED.I-syncozymes iphuhliswe i-15 imine reductases (i-numbIRED ES-IRED-101-ES-IRED-115), enokusetyenziswa ngokubanzi ekunciphiseni i-regioselective kunye ne-stereoelective ye-imines ukulungiselela i-chiral amines.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitrile reductase (NRED)
Malunga neNitrile reductase
Kukho uhlobo lwe-3 yemveliso ye-enzyme ye-NRED (Inombolo njenge-ES-NRED101~ ES-NRED103) ephuhliswe ngu-SyncoZymes.I-NRED inokubangela ukuncipha kweqela le-nitrile kwi-amine.Kwinkqubo ye-catalysis, i-NADPH iyafuneka njenge-hydrogen transporter.
Uhlobo lokusabela lwe-Nitrile reductasecatalytic
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
Malunga nePhenylalanine dehydrogenase
ES-PDH: Iklasi ye-oxidoreductase.Ukusabela okufanelekileyo kunokubangela i-oxidative deamination ye-L phenylalanine ityuwa phambi kwe-NAD ukuvelisa ityuwa ye-phenylpyruvate, kunye ne-reverse reaction can catalyze synthesis ye-amino acid ityuwa ehambelana netyuwa ye-phenylpyruvate.I-Syncozymes iphuhlise izinto ze-8 ze-phenylalanine dehydrogenase (inombolo ye-ES-PDH-101~ES-PDH-108).I-ES-PDH ingasetyenziselwa ukulungiselela ityuwa ye-phenylalanine okanye ityuwa ye-amino acid ehambelanayo esuka kwityuwa ye-phenylpyruvic okanye i-derivatives.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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ILeucine Dehydrogenase (LeuDH)
Malunga neLeucine dehydrogenase
Kukho uhlobo lwe-1 lwemveliso ye-enzyme ye-LeuDH (Inombolo njenge-ES-LeuDH-101) ephuhliswe ngu-SyncoZymes.I-LeuDH inokwenza i-ammoniation yokunciphisa i-4-methylbutanoic acid (ityuwa) kwi-L-leucine okanye i-oxidation ye-leucine kwi-4-methylbutanoic acid.I-ES-LeuDH inokwenza kwakhona i-amination yokunciphisa i-α-keto acids enesakhiwo esifanayo ukulungiselela i-amino acid derivatives ehambelanayo.Kwinkqubo ye-catalysis, i-NADH iyimfuneko njenge-hydrogen transporter.
Leucine dehydrogenasecatalytic reaction type
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Threonine deaminase (TDA)
Malunga neThreonine deaminase
I-ES-TDA (i-Threonine deaminase): iprotheni ye-pyridoxal phosphate eyenza i-deamination ye-threonine ivelise i-2-ketobutyric acid kunye ne-ammonia.I-Pyridoxal 5-phosphate iyimfuneko njenge-coenzyme kwinkqubo ye-catalytic.Kukho kuphela uhlobo lwe-1 yemveliso ye-enzyme ye-TDA (Inombolo njenge-ES-TDA) ephuhliswe yi-SyncoZymes, engasetyenziselwa ukulungisa i-2-ketobutyric acid okanye i-derivatives yayo kwi-threonine.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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IAmine Dehydrogenase (AmDH)
Malunga neAmine Dehydrogenase
I-ES-AmDH (i-Amine Dehydrogenase): i-enzyme enokuthi ibangele i-ammoniation yeqela le-carbonyl kwaye iyinciphise kwiqela le-amino.Yi-enzyme exhomekeke kwi-coenzyme ye-NADH, kwaye i-NADH isebenza njenge-hydrogen transmitter.Kukho iintlobo ezi-4 zeemveliso ze-enzyme ye-AmDH (Inombolo njenge-ES-AmDH101～ES-AmDH104) ephuhliswe yi-SyncoZymes, enokusetyenziswa kwi-regioselective okanye i-stereoelective reductive amination of aldehydes and ketones.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
