-
I-D-Amino acid dehydrogenase (D-AADH)
Malunga ne-D-Amino acid dehydrogenase
I-ES-D-AADH (i-D-Amino acid dehydrogenase): i-enzyme enokunciphisa i-2-keto acid ibe yi-D-amino acid ehambelanayo. I-reaction ifuna i-NADP(H) kunye ne-inorganic ammonia donor (efana ne-ammonia okanye i-ammonium ion). Kukho iintlobo ezili-17 ze-D-amino acid dehydrogenases (Inombolo njenge-ES-DAADH-101~ ES-DAADH-117) eyenziwe yiSyncoZymes.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Esterase kunye neLipase (PLE kunye neCALB)
Malunga ne-Esterase kunye neLipase
Ii-ES-PLE: Udidi lwee-hydrolases ezikhuthaza ukwakheka nokuqhekeka kwee-ester bonds. Zingathatha inxaxheba kwiintlobo ezininzi zeempendulo ze-biochemical, ezifana ne-esterification, i-transesterification kunye ne-hydrolysis. Zisetyenziswa kakhulu kwiindawo ezininzi ezifana nokulungiswa kokutya, ishishini leekhemikhali, i-biomedicine, amayeza e-chiral kunye nonyango lokusingqongileyo.
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Epoxide hydrolase (EH)
Malunga ne-epoxide hydrolase
I-EH yi-ether hydrolase evuselela i-stereoselective hydrolysis yee-racemic epoxides ukuvelisa i-1, 2-diol kunye nee-epoxides ezisebenzayo, ezinokusetyenziselwa isisombululo se-chiral seepoxides okanye ukulungiswa kwee-chiral diols. Zisetyenziswa kakhulu kwezonyango nakwamanye amasimi. Kukho iintlobo ezi-3 zeemveliso ze-epoxide hydrolases (Inombolo njenge-ES-EH-101～ES-EH-103) eziphuhliswe yiSyncoZymes. I-ES-EH sisixhobo esiluncedo sokuvuselela ukwenziwa kwee-chiral alcohols ngokusebenzisa i-stereoselective hydrolysis yee-aliphatic kunye nee-aromatic epoxides.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-formate dehydrogenase (FDH)
Malunga neFormate dehydrogenase
I-ES-FDH (i-Formate dehydrogenase): I-FDH ikhuthaza ukususwa kwe-hydrogenation ye-ammonium formate ukuze ivelise i-carbon dioxide kunye ne-ammonia, kwaye inciphise i-NAD ibe yi-NADH nge-NAD njenge-electron receptor. I-FDH idla ngokusetyenziselwa ukuvuselelwa kwe-coenzyme NADH. Kukho iintlobo ezine zeemveliso ze-enzyme ze-FDH (ES-FDH-101~ES-FDH-104) ezenziwe yiSyncoZymes, phakathi kwazo i-ES-FDH102 inomsebenzi ophezulu kwaye yeyona FDH icetyiswayo kakhulu.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-glucose dehydrogenase (GDH)
Malunga neGlucose dehydrogenase
I-ES-GDH (i-glucose dehydrogenase): I-GDH ivuselela ukususwa kwe-glucose ukuze ivelise i-gluconic acid (i-lactone), kwaye inciphise i-NAD(P)+ ibe yi-NAD(P)H, kunye ne-NAD(P)+ njenge-electron receptor. I-GDH idla ngokusetyenziselwa ukuvuselelwa kwe-coenzyme NAD(P)H kwiindawo ze-biocatalysis kunye nezinye ii-enzyme eziphambili. Kukho iintlobo ezili-10 zeemveliso ze-enzyme ze-GDH (ES-GDH-101~ES-GDH-110) ezenziwe yiSyncoZymes, phakathi kwazo i-ES-GDH110 inomsebenzi ophezulu kwaye yeyona GDH icetyiswayo kakhulu.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Monoamine oxidase (MAO)
Malunga neMonoamine oxidase
I-ES-MAO (i-Monoamine oxidase): I-MAO ivuselela i-oxidative deamination ye-monoamines ukuvelisa i-hydrogen peroxide, i-ammonia kunye ne-aldehydes ehambelanayo. Kwinkqubo ye-catalytic, i-oksijini iyimfuneko njenge-oxidant. Kukho iintlobo ezi-6 zeemveliso ze-enzyme ze-MAO (Inombolo njenge-ES-MAO-101 ~ ES-MAO-106) eziphuhliswe yiSyncoZymes, ezinokusetyenziswa kwi-oxidative deamination ye-monoamine compounds.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Lactate Dehydrogenase (LDH)
Malunga neLactate dehydrogenase
Kukho uhlobo olunye lwemveliso ye-enzyme ye-LDH (iNombolo njenge-ES-LDH) eyenziwe yiSyncoZymes. I-LDH inokwenza i-pyruvate inciphe ibe yi-L-lactic acid, okanye inciphe nezinye ii-α-keto acids ezifanayo. Kwinkqubo ye-catalysis, i-NADH iyimfuneko njengomthuthi we-hydrogen.
Uhlobo lokusabela kwe-lactate dehydrogenasecatalytic
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Imine reductase (IRED)
Malunga ne-Imine reductase
I-ES-IRED: Ludidi lwee-enzymes ezikhuthaza ukunciphisa i-C=N bond kwi-CN bond. Yeye-redox enzyme, ene-coenzyme NADPH yokuthutha i-hydrogen. Ngokwendlela ezithandwa ngayo iimveliso ze-chiral, zinokwahlulwa zibe yi-R-IRED kunye ne-S-IRED. I-Syncozymes yenze i-15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), ezingasetyenziswa kakhulu ekunciphiseni i-regioselective kunye ne-stereoselective ye-imines ukulungiselela i-chiral amines.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Nitrile reductase (NRED)
Malunga ne-Nitrile reductase
Kukho iintlobo ezintathu zemveliso ye-enzyme ye-NRED (Inombolo njenge-ES-NRED101~ ES-NRED103) eyenziwe yiSyncoZymes. I-NRED inokwenza i-catalyst inciphise iqela le-nitrile ibe yi-amine. Kwinkqubo ye-catalysis, i-NADPH iyadingeka njengomthuthi we-hydrogen.
Uhlobo lokusabela lwe-Nitrile reductasecatalytic
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Leucine Dehydrogenase (LeuDH)
Malunga neLeucine dehydrogenase
Kukho uhlobo olunye lwemveliso ye-enzyme yeLeuDH (Inombolo njenge-ES-LeuDH-101) eyenziwe yiSyncoZymes. I-LeuDH inokwenza i-ammoniation ye-4-methylbutanoic acid (ityuwa) ibe yi-L-leucine okanye i-oxidation ye-leucine ibe yi-4-methylbutanoic acid. I-ES-LeuDH ingenza i-α-keto acids ibe yi-reductive amination enesakhiwo esifanayo ukulungiselela i-amino acid derivatives ehambelanayo. Kwinkqubo ye-catalysis, i-NADH iyimfuneko njengomthuthi we-hydrogen.
Uhlobo lwempendulo ye-Leucine dehydrogenasecatalytic
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Threonine deaminase (TDA)
Malunga neThreonine deaminase
I-ES-TDA (iThreonine deaminase): iproteni ye-pyridoxal phosphate evuselela ukususwa kwe-threonine ukuze kuveliswe i-2-ketobutyric acid kunye ne-ammonia. I-Pyridoxal 5-phosphate iyimfuneko njenge-coenzyme kwinkqubo ye-catalytic. Kukho uhlobo olunye kuphela lwemveliso ye-enzyme ye-TDA (iNombolo njenge-ES-TDA) eyenziwe yiSyncoZymes, enokusetyenziswa ukulungiselela i-2-ketobutyric acid okanye izinto eziphuma kuyo kwi-threonine.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
-
I-Amine Dehydrogenase (AmDH)
Malunga ne-Amine Dehydrogenase
I-ES-AmDH (i-Amine Dehydrogenase): i-enzyme enokushukumisa i-ammoniation yeqela le-carbonyl ize iyinciphise ibe liqela le-amino. Yi-enzyme exhomekeke kwi-coenzyme NADH, kwaye i-NADH isebenza njengomthumeli we-hydrogen. Kukho iintlobo ezine zeemveliso ze-enzyme ze-AmDH (Inombolo njenge-ES-AmDH101 ~ ES-AmDH104) eyenziwe yiSyncoZymes, engasetyenziswa kwi-regioselective okanye stereoselective reductive amination ye-aldehydes kunye neeketones.
Uhlobo lwempendulo ye-Catalytic:
Iselfowuni/iWechat/iWhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
