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IiOxynitrilases (HNL)
Malunga ne-oxynitrilases
I-ES-HNLs: I-enzyme yeklasi eyenza i-enantioselectively i-catalyze ukongezwa kwe-HCN kwi-aldehydes (i-ketones) ukufumana i-R okanye i-S yohlobo lwe-cyanide alcohols, enokuguqulwa ngokulula kwiindidi ezininzi zeziyobisi okanye izibilini zeziyobisi ngokusebenzisa indlela yekhemikhali.
Kukho iintlobo ze-29 zeemveliso ze-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) ephuhliswe ngu-SyncoZymes.I-SZ-HNL sisixhobo esiluncedo kwi-regio- kunye ne-stereo- selective synthesis ye (R) -cyanohydrins okanye (S) -cyanohydrins evela kwiindidi ze-aldehydes ezivumba, i-aliphatic kunye ne-heterocyclic okanye i-ketones.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Nitro reductase (NTR)
Malunga ne-nitro reductase
I-ES-NTRs: Ngaba i-flavoenzymes eyenza ukunciphisa i-NAD (P) H-exhomekeke kumaqela e-nitro kwiikhompawundi ze-nitroaromatic kunye ne-nitroheterocyclic kwi-hydroxylamino kunye / okanye i-amino derivatives.Zisetyenziswa ngokubanzi kwi-organic synthesis ye-hydroxylamine enevumba elimnandi kunye ne-amine enuka kamnandi, unyango lwethumba, ubhaqo lwebhayoloji kunye nokuthotywa kwezinto ezingcolisa indalo.Kukho iintlobo ezili-12 zeemveliso ze-Nitro reductase (NTR) (Inombolo njenge-ES-NTR-101~ES-NTR-112) ephuhliswe ngu-SyncoZymes.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Aldolase (DERA)
I-ES-DERAs: Inokwenza ngokufanelekileyo ukongezwa kwe-stereoelective yee-ketones zabaxhasi kwi-receptor aldehydes.Ngaphezu koko, ukusabela kunokwenziwa kwisisombululo esimanzi se-pH engathathi hlangothi ngaphandle kwamanyathelo okukhusela akhethekileyo.Bangabeklasi I aldolase, eyenza isiseko sikaShiff kwinkqubo ye-catalytic.I-substrate ihlanganiswe ngokubambisana kunye neqela le-amino lendawo esebenzayo ukuqalisa ukuphuka kunye nokwakhiwa kwebhondi.Umahluko phakathi kwe-DERAs kunye nezinye ii-aldolases kukuba ii-substrates ezizenza zi-aldehydes kwaye zinokungena kwi-aldehydes condensation eqhubekayo.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Cytochrome P450 monooxygenase (CYP)
Malunga neCYP
I-ES-CYPs: Iklasi ye-redox enzymes kunye ne-mercaptan-heme njengeziko elisebenzayo lokunyusa ukuhanjiswa kwe-oxygen.Ziyi-oxygen e-terminal kwaye idinga i-heme ukuze isebenze i-oxygen.
I-Cytochrome P450 monooxygenase yenza i-oxidation, i-epoxidation kunye ne-hydroxylation ye-alkyl, i-hydroxylation kunye ne-oxidation ye-ammonia, i-oxidation yesulfure, i-dealkylation (i-oxygen, i-sulfur, i-ammonia), i-oxidative dehydrogenation, i-deamination kunye ne-dehalogenation.
Kukho iintlobo ezisi-8 zeemveliso ze-cytochrome P450 monooxygenase (Inombolo njenge-ES-CYP-101～ES-CYP-108) ephuhliswe ngu-SyncoZymes.Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Alcohol oxidase (AOX)
Malunga ne-alcohol oxidase
I-ES-AOXs: Ezi enzymes ziyakwazi ukwenza i-oxidation yee-alcohols ezinamafutha okanye i-aryl-alcohols ukwenza i-aldehydes.Basebenzisa ioksijini yemolekyuli kodwa ayifuni icofactor eyongeziweyo ngaphandle, kunye nehydrogen peroxide iveliswa.
Kukho iintlobo ezi-6 zeemveliso ze-alcohol oxidases (Inani njenge-ES-AOX-101~ES-AOX-106) ephuhliswe yi-SyncoZymes.I-ES-AOX101 kunye ne-ES-AOX102 zikhetha i-aliphatic alcohol substrates, i-ES-AOX103~ ES-AOX105 ikhetha i-alcohol substrates enuka kamnandi, kwaye i-ES-AOX106 yi-cholesterol oxidase.I-SZ-AOX sisixhobo esiluncedo sokwenza i-oxidation yee-alcohols ezinamafutha okanye i-aryl-alcohols ukuvelisa i-aldehydes.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-D-Amino acid dehydrogenase (D-AADH)
Malunga ne-D-Amino acid dehydrogenase
I-ES-D-AADH (i-D-Amino acid dehydrogenase): i-enzyme enokunciphisa i-2-keto acid kwi-D-amino acid ehambelanayo.Ukusabela kufuna i-NADP (H) kunye nomxhasi we-ammonia we-inorganic (njenge-ammonia okanye i-ammonium ion).Kukho iintlobo ze-17 ze-D-amino acid dehydrogenases (Inombolo njenge-ES-DAADH-101~ ES-DAADH-117) ephuhliswe yi-SyncoZymes.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Esterase&Lipase (PLE&CALB)
Malunga ne-Esterase&Lipase
I-ES-PLEs: Iklasi ye-hydrolases eyenza ukubunjwa kunye nokuphulwa kweebhondi ze-ester.Banokuthatha inxaxheba kwiindidi ezininzi ze-biochemical reactions, ezifana ne-esterification, i-transesterification kunye ne-hydrolysis.Zisetyenziswa ngokubanzi kwiinkalo ezininzi ezifana nokulungiswa kokutya, ishishini lemichiza, i-biomedicine, amayeza e-chiral kunye nonyango lokusingqongileyo.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Epoxide hydrolase (EH)
Malunga ne-epoxide hydrolase
I-EH yi-ether hydrolase eyenza i-stereoelective hydrolysis ye-racemic epoxides ukuvelisa i-1, i-2-diol kunye ne-optical active epoxides, engasetyenziselwa ukulungiswa kwe-chiral ye-epoxides okanye ukulungiswa kwe-chiral diols.Zisetyenziswa kakhulu kwezamayeza nakwezinye iindawo.Kukho iintlobo ezi-3 zeemveliso ze-epoxide hydrolases (Inani njenge-ES-EH-101～ES-EH-103) ephuhliswe yi-SyncoZymes.I-ES-EH sisixhobo esiluncedo sokwenza i-synthesis ye-chiral alcohols ngokusebenzisa i-stereoselective hydrolysis ye-aliphatic kunye ne-aromatic epoxides.
Uhlobo lwe-Catalytic reaction:
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I-imeyile:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Malunga neFomate dehydrogenase
I-ES-FDH (i-Formate dehydrogenase): I-FDH yenza i-dehydrogenation ye-ammonium formate ukuvelisa i-carbon dioxide kunye ne-ammonia, kunye nokunciphisa i-NAD kwi-NADH kunye ne-NAD njenge-electron receptor.I-FDH isoloko isetyenziselwa ukuhlaziywa kwe-coenzyme NADH.Kukho iintlobo ezi-4 zeemveliso ze-enzyme ze-FDH (ES-FDH-101~ES-FDH-104) eziphuhliswe yi-SyncoZymes, phakathi kwazo i-ES-FDH102 inomsebenzi ophezulu kwaye yeyona FDH ecetyiswayo.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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IGlucose dehydrogenase (GDH)
Malunga neGlucose dehydrogenase
I-ES-GDH (i-Glucose dehydrogenase): I-GDH ivuselela i-dehydrogenation ye-glucose ukuvelisa i-gluconic acid (lactone), kunye nokunciphisa i-NAD (P) + kwi-NAD (P) H, kunye ne-NAD (P) + njenge-electron receptor.I-GDH isoloko isetyenziselwa ukuhlaziywa kwe-coenzyme NAD (P) H kwiinkalo ze-biocatalysis kunye nezinye i-enzyme ephambili.Kukho iintlobo ze-10 zemveliso ye-enzyme ye-GDH (ES-GDH-101~ES-GDH-110) ephuhliswe yi-SyncoZymes, phakathi kwayo i-ES-GDH110 inomsebenzi ophezulu kwaye iyona GDH ekhuthazwayo.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Monoamine oxidase (MAO)
Malunga neMonoamine oxidase
I-ES-MAO (i-Monoamine oxidase): I-MAO yenza i-oxidative deamination ye-monoamines ukuvelisa i-hydrogen peroxide, i-ammonia kunye ne-aldehydes ehambelanayo.Kwinkqubo ye-catalytic, i-oksijini iyimfuneko njenge-oxidant.Kukho iintlobo ze-6 zeemveliso ze-enzyme ze-MAO (Inombolo njenge-ES-MAO-101～ES-MAO-106) ephuhliswe yi-SyncoZymes, enokusetyenziswa kwi-oxidative deamination ye-monoamine compounds.
Uhlobo lwe-Catalytic reaction:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
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I-Lactate Dehydrogenase (LDH)
Malunga neLactate dehydrogenase
Kukho uhlobo lwe-1 lwemveliso ye-enzyme ye-LDH (Inombolo njenge-ES-LDH) ephuhliswe yi-SyncoZymes.I-LDH inokubangela ukunciphisa i-pyruvate kwi-L-lactic acid, okanye ukunciphisa ezinye i-α-keto acids ezifanayo.Kwinkqubo ye-catalysis, i-NADH iyimfuneko njenge-hydrogen transporter.
Lactate dehydrogenasecatalytic reaction type
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyile:lchen@syncozymes.com
